011-703-527-3887 . ChEBI. CHEMTREC … A 0.290 gram sample of a weak base is titrated with a 0.150 M HCl solution. In agarose, Cresol Red runs with an apparent molecular size of approximately 125 bp DNA. Cresol Red, 0.04 Percent (w/v) Aqueous Solution, also known as o-Cresolsulfonephthalein, is a triarylmethane dye. Beilstein/REAXYS Number 343399 . MDL number MFCD00005878. Dissolve 60 g of sucrose in 80 ml distilled water on magnetic stirrer. The Occupational Safety and Health Administration has set a permissible exposure limit at 5 ppm (22 mg/m3) over an eight-hour time-weighted average, while the National Institute for Occupational Safety and Health recommends a limit of 2.3 ppm (10 mg/m3). Emergency Phone Number: (800) 424-9300 . [citation needed] About half of the world's supply of cresols are extracted from coal tar. Like other types of phenols, they are slowly oxidized by long exposure to air, and the impurities often give samples of cresols a yellowish to brownis… The mode of action of this disinfectant is to disrupt the … Cresol Red sodium salt. LabChem solutions u P-Cresol | CH3C6H4OH or C7H8O | CID 2879 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. Cresol red (full name: o-cresolsulfonephthalein) is a triarylmethane dye frequently used for monitoring the pH in aquaria. Effects observed in people include irritation and burning of skin, eyes, mouth, and throat; abdominal pain and vomiting; heart damage; anemia; liver and kidney damage; facial paralysis; coma; and death. 382.43. Pittsburgh, PA 15238 . Sigma-Aldrich offers a number of Cresol red products. Cresol Red sodium salt acts as a constituent of polymerase chain reaction reagent systems. Except where otherwise noted, data are given for materials in their standard state (at … Properties. Chemical waste generators must also consult local, regional, and national hazardous waste regulations to ensure complete and accurate classification. Back to Top. Company Identification: LabChem Inc . COVID-19 is an emerging, rapidly evolving situation. Like other types of phenols, they are slowly oxidized by long exposure to air, and the impurities often give samples of cresols a yellowish to brownish red tint. P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362, P403+233, P405, P501: NFPA 704 (fire diamond) 0. Company Phone Number: (412) 826-5230 . Cresol red can be used in many common molecular biology reactions in place of other loading dyes. Get medical attention. Empirical Formula (Hill Notation) C 21 H 18 O 5 S . 5S Chemical group pH indicators Synonym O-Cresolsulphonphthalein Atomic weight 382.44 Weight per litre 0.98kg Appearance Reddish-brown crystalline powder. Cresol red solution 0.04 wt. Solubility. Company Identification: LabChem Inc . Chemical name. 0. Contents. soln. The name cresol reflects their structure, being phenols, and their traditional source, creosote. [5][6], Cresols are precursors or synthetic intermediates to other compounds and materials, including plastics, pesticides, pharmaceuticals, and dyes. Aside from these effects, very little is known about the effects of breathing cresols, for example, at lower levels over longer times. The monoalkylated derivatives undergo coupling to give an extensive family of diphenol antioxidants. Ingesting high levels results in kidney problems, mouth and throat burns, abdominal pain, vomiting, and effects on the blood and nervous system. Beilstein/REAXYS Number 343399 . No human or animal studies have shown harmful effects from cresols on reproduction. Short-term and long-term studies with animals have shown similar effects from exposure to cresols. Contributors. Depending on the temperature, cresols can be solid or liquid because they have melting points not far from room temperature. First-aid measures Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Cresol Red, sodium salt, water soluble, indicator Revision Date 18-Jan-2018 13. Product identifier . Empirical Formula (Hill Notation) C 21 H 18 O 5 S . In its chemical structure, a molecule of cresol has a methyl group substituted onto the ring of phenol. Cresol Red, Indicator Grade, Pure, ACROS Organics™ ... Solubility: Solubility in water: soluble. 58 / Monday, March 26, 2012 / Rules and Regulations Date of issue: 12/23/2014 Version: 1.0 12/23/2014 EN (English US) Page 1 SECTION 1: Identification of the substance/mixture and of the company/undertaking . Get medical attention. Ambient temperatures. A solution is yellow when both methyl yellow and cresol purple are added. Molecular Weight 382.43 . Occupational Safety and Health Administration, National Institute for Occupational Safety and Health, "Making carbon nanotubes as usable as common plastics: Researchers discover that cresols disperse carbon nanotubes at unprecedentedly high concentrations", "Additive-free carbon nanotube dispersions, pastes, gels, and doughs in cresols", Documentation for Immediately Dangerous To Life or Health Concentrations (IDLHs) - Cresol (o, m, p isomers), https://en.wikipedia.org/w/index.php?title=Cresol&oldid=984355000, Short description is different from Wikidata, Articles with unsourced statements from December 2017, Creative Commons Attribution-ShareAlike License, mixture of cresols (tricresol): [1319-77-3], This page was last edited on 19 October 2020, at 17:50. Inhalation Remove from exposure, lie down. At what pH is cresol red, orange in color? MDL number MFCD00001618 14. Helmut Fiegein "Cresols and Xylenols" in Ullmann's Encyclopedia of Industrial Chemistry" 2007; Wiley-VCH, Weinheim. MDL number MFCD00005878. Company Phone Number: (412) 826-5230 . InChI=1S/C21H18O5S/c1-13-11-15(7-9-18(13)22)21(16-8-10-19(23)14(2)12-16)17-5-3-4-6-20(17)27(24,25)26-21/h3-12,22-23H,1-2H3, InChI=1/C21H18O5S/c1-13-11-15(7-9-18(13)22)21(16-8-10-19(23)14(2)12-16)17-5-3-4-6-20(17)27(24,25)26-21/h3-12,22-23H,1-2H3, Cc1cc(ccc1O)/C(=C/2C=CC(=O)C(=C2)C)c3ccccc3OS(O)=O, Except where otherwise noted, data are given for materials in their, Learn how and when to remove this template message, Cresol Red at OpenWetWare life scientists' wiki, https://en.wikipedia.org/w/index.php?title=Cresol_Red&oldid=966465054, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Articles lacking sources from September 2007, Creative Commons Attribution-ShareAlike License, This page was last edited on 7 July 2020, at 08:15. Soluble in water, dilute alcohols, acids, alkalies and ethanol. There are three forms (isomers) of cresol: ortho-cresol (o-cresol), meta-cresol (m-cresol), and para-cresol (p-cresol). 1.1. Cresol red sodium salt can be used in many common molecular biology reactions in place of other loading dyes. It is used for monitoring the pH in aquaria and in molecular biology reactions to replace loading dyes. Red solution Solubility Powder soluble in water, alcohol and dilute acids and alkalis. Phenol is moderately soluble in water - about 8 g of phenol will dissolve in 100 g of water. Cresol red is a member of the class of 2,1-benzoxathioles that is 2,1-benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 4-hydroxy-5-methylphenyl groups. 1. Another method entails methylation of phenol with methanol over a solid acid catalyst, often comprising magnesium oxide or alumina. 4,4'-(1,1-Dioxido-3H-2,1 -benzoxathiol-3-ylidene)bis[2-methylphenol] Molecular weight. Give a pH range for this solution. MW: 404.41 Applications. 62625-29-0 : Cresol red… 1733-12-6 . C 2 1 H 1 7 NaO 5 S. Formula Weight. Molecular formula. room temp SMILES string [Na+].Cc1cc(ccc1O)\C(=C2/ C=CC(=O)C(C)=C2)c3ccccc3S ([O-])(=O)=O … It is useful as a pH indicator with color changes with pH 0.2 - pH 1.8 and pH 7.1 - 8.8. 404.42 Melting point. CAS# Chemical Name: Percent. Temperatures above 300 °C are typical. Anisole converts to cresols under these conditions. These antioxidants are valued because they are relatively low in toxicity and nonstaining. Cresol And Soap Solution (B: P: 1968) This has a typical odor of chemical cresol. Formocresol, a preparation of formalin and cresol, is also used as a root canal medicament and for pulpotomy of primary teeth. MSDS Name: Cresol Red – Thymol Blue, Aqueous . Chemical Properties. Formula. When dissolveing cresol red, use only minimum amount of methanol. Store at Room Temperature. % in H 2 O CAS Number 1733-12-6. 77, No. EC Number 217-064-2. In a 1% agarose gel, it runs approximately at the size of a 125 base pair (bp) DNA molecule (it depends on the concentration of buffer and other component). This is effective almost on all the microbes. These forms occur separately or as a mixture, which can also be called cresol or more specifically, tricresol. [1] It is a weak acid with p K a = 8.00 at 20 °C (68 °F). It has a role as an acid-base indicator, a dye and a two-colour indicator. EINECS. Emergency Phone Number: (800) 424-9300 . Cresol Red – Thymol Blue, Aqueous . When cresols are inhaled, ingested, or applied to the skin, they can be very harmful. Cresol Red Indicator Solution . Molecular Weight 382.43 . Cresol red stock buffer 60% sucrose 0.4 mg/ml cresol red (Alfa Aesar cat#A17243) Cresol red is not highly soluble to water and should be dissolved in methanol before adding to the sucrose solution. Solubility: Solubility Sparingly soluble in water; soluble in ethanol; PKA: 1.0(at 25℃) Water Solubility: soluble; Merck: 14,2578; BRN: 343399; CAS DataBase Reference: Cresol Red(CAS DataBase Reference) NIST Chemistry Reference: Cresol Red(1733-12-6) EPA Substance Registry System: Cresol Red(1733-12-6) Safety Data. Further, it plays an important role in molecular biology reactions in place of other loading dyes. Cresol Red does not inhibit Taq polymerase to the same degree as other common loading dyes. 200 William Pitt Way . [9], Group of chemical compounds, types of methylphenol. Skin Contact Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes. Cresol Red sodium salt acts as a constituent of polymerase chain reaction reagent systems. Cresol Red, 0.04% Aqueous Safety Data Sheet according to Federal Register / Vol. 263-654-8. 7732-18-5 >99 ; Water . Main ChemSpider page; Molecular formula: C 21 H 17 NaO 5 S; Molar mass: 404.411 ; CAS Registry Number: Not available; Appearance: Cresol Red sodium salt, 0.04% w/v aq. They are a widely occurring natural and manufactured group of aromatic organic compounds, which are categorized as phenols (sometimes called phenolics). 200 William Pitt Way . soln. Its solubility is 0.77 grams per liter (g/l) in water and 2.9 g/l in ethanol . The spectrophotometric methods depend on the formation of chloroform-soluble ion-association complexes of cinnarizine with thymol blue (TB) and with cresol red in sodium acetate–acetic acid buffer of pH 3.6 for TB and in potassium chloride–hydrochloric acid buffer at pH 1.6 for cinnarizine with absorption maxima at 405 and 403 nm for TB and cinnarizine, respectively. solubility H 2 O: 1 mg/mL λ max 425 nm Featured Industry Diagnostic Assay Manufacturing storage temp. Get the latest public health information from CDC: https://www.coronavirus.gov. Cresol Red Revision Date 18-Jan-2018 Cresol red 1733-12-6 100 4. 58 / Monday, March 26, 2012 / Rules and Regulations Date of issue: 12/23/2014 Revision date: 05/03/2017 Supersedes: 12/23/2014 Version: 1.1 05/03/2017 EN (English US) Page 1 SECTION 1: Identification 1.1. Cresol red (sodium salt) Last updated; Save as PDF Page ID 75505; No headers. MDL. C and T manufactures Cresol and Soap solution according to bp1968 standards. Molecular Weight 382.43 . The rest is produced by hydrolysis of chlorotoluenes or the related sulfonates. Cresols (also hydroxytoluene) are organic compounds which are methylphenols. Phenol is somewhat soluble in water because of its ability to form hydrogen bonds with the water. PubChem Substance ID 24847173 Depending on the temperature, cresols can be solid or liquid because they have melting points not far from room temperature. Cresol red (full name: o-cresolsulfonephthalein) is a triarylmethane dye frequently used for monitoring the pH in aquaria. ca 250° dec. EC Index Number 217-064-2 Subject:* missing translation for 'pleaseEnterSubject'. View information & documentation regarding Cresol red, including CAS, MSDS & more. Ph Eur Synonym: Cresol red, o-Cresolsulfonphthalein CAS Number 1733-12-6. Cresol red can also be used as an electrophoretic color marker to monitor the process of agarose gel electrophoresis and polyacrylamide gel electrophoresis. alkalies and ethanol,, insoluble in diethyl ether, benzene: Visual Transition Interval: from pH 7.0 (orange) to pH 8.8 (purple) Color: Brown-Red or Green : SDS. The top layer is a solution of phenol in water, and the bottom one a solution of water in phenol. What color is a solution of 0.10 M NaOH when 1 drop of cresol purple is added? Do not autoclave. However, little is known about its effect on cardiovascular system. CAS Number. Chemical structure. Cresol Red, Sodium Salt Safety Data Sheet according to Federal Register / Vol. acids, dil. Cresol red does not inhibit Taq polymerase to the same degree as other common loading dyes. Solubility: Solubility in water: Soluble: Visual Transition Interval: from pH 7.0 (yellow) to pH 8.8 (purple) Color: Brown: Quantity: 5g: Chemical Name or Material: Cresol Red, sodium salt acids, and dil. Storage & Sensitivity. Cresols (also hydroxytoluene) are organic compounds which are methylphenols. It is not known what the effects are from long-term ingestion or skin contact with low levels of cresols. Buy Cresol red sodium salt (CAS 62625-29-0), a pH indicator with color changes with pH 0.2 - pH 1.8 and pH 7.1 - 8.8, from Santa Cruz. CHEMTREC Phone Number: (800) 424-9300 or . It is a 2,1-benzoxathiole, an arenesulfonate ester, a polyphenol and a sultone. alkalis. Cresols have an odor characteristic to that of other simple phenols, reminiscent to some of a "coal tar" smell. Phenol red exists as a red crystal that is stable in air. Breathing high levels of cresols for a short time results in irritation of the nose and throat. If you try to dissolve more than this, you get two layers of liquid. Solubility in water. Catalog Numbers: LC13540 . Section 1 - Chemical Product and Company Identification . They are a widely occurring natural and manufactured group of aromatic organic compounds, which are categorized as phenols (sometimes called phenolics). Cresol is a well-known environmental pollutant, toluene metabolite, uremic toxicant and accidental poisoning product. Synonyms: None . Empirical Formula (Hill Notation) C 21 H 18 O 5 S . Cresol Red does not inhibit Taq polymerase. Disposal considerations Waste Disposal Methods Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. Other solubilities: soluble in dil. Cresol red indicator Reag. C 21 H 18 O 5 S. Storage instructions. Soluble in water (slightly at 20°C), 50% ethanol (0.1%), dil. Bromophenol blue and xylene cyanol can also be used for this purpose. Section 2 - Composition, Information on Ingredients. Solubility in water < 0.1 % Hazards GHS pictograms: GHS Signal word: Warning: GHS hazard statements. MFCD00001618. ; Cresol Red sodium salt, 0.04% w/v aq. Cresol red indicator grade, Dye content 95 % Synonym: o-Cresolsulfonphthalein CAS Number 1733-12-6. H315, H319, H335: GHS precautionary statements. p-Cresol is consumed mainly in the production of antioxidants, such as butylated hydroxytoluene (BHT). [6], Most recently, cresols have been used to create a breakthrough in manufacturing carbon nanotubes at scale that are separated and not twisted, without additional chemicals that change the surface properties of the nanotubes.[7][8]. 77, No. 9. Skin contact with high levels of cresols can burn the skin and damage the kidneys, liver, blood, brain, and lungs. Pittsburgh, PA 15238 . 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